LDL Cholesterol
Disclaimer: Information on this page is for educational purposes. Consult a physician to interpret your test results. Health Vault helps track biomarker trends but does not replace medical advice.
What This Test Measures
LDL is the 'bad' cholesterol and main contributor to atherosclerotic plaque. LDL reduction is proven for primary and secondary CAD prevention.
Targets are individualized: very high-risk patients aim for <1.4 mmol/L (<55 mg/dL).
Calculated via Friedewald equation or measured directly.
Normal Ranges
| Group | Reference Range |
|---|---|
| Men | <100 mg/dL (<2.6 mmol/L) for moderate risk |
| Women | <100 mg/dL |
| Children | <110 mg/dL |
Reference ranges may vary by laboratory and assay method.
Causes of High Levels
- High saturated fat intake
- Familial hypercholesterolemia
- Hypothyroidism
- Diabetes
- Nephrotic syndrome
Causes of Low Levels
- Hyperthyroidism
- Malabsorption
- Advanced liver disease
- Acute illness
Test Preparation
- Fasting 9–12 hours
- Stable diet for 2 weeks before testing
Related Biomarkers
| Biomarker | Relationship |
|---|---|
| HDL Cholesterol | Total/HDL ratio |
| Triglycerides | VLDL component |
| Total Cholesterol | Overall lipid status |
FAQ
How often should I take this test?
Annually; on statins — every 6–12 months.
What should I do if my result is abnormal?
LDL above target — discuss diet, exercise, and statin therapy with your cardiologist.
Last updated: June 2026