BNP / NT-proBNP — Heart Failure Marker: Range and Interpretation

Updated: June 2025

BNP (Brain Natriuretic Peptide) and NT-proBNP are markers of heart failure. Released by cardiomyocytes in response to volume and pressure overload. Used for diagnosis and monitoring of CHF.

Reference Range

BNP: < 100 пг/мл; NT-proBNP: < 125 пг/мл (до 75 лет), < 450 пг/мл (>75 лет)

Causes of Elevation

Chronic heart failure
Acute coronary syndrome
Left ventricular hypertrophy
Pulmonary hypertension
Tachyarrhythmias
Renal failure
Advanced age (physiological elevation)

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