Total Protein
Disclaimer: Information on this page is for educational purposes. Consult a physician to interpret your test results. Health Vault helps track biomarker trends but does not replace medical advice.
What This Test Measures
Total protein includes albumin and globulins (immunoglobulins, transport proteins). It reflects hepatic synthesis and immune status.
Elevation is often linked to chronic inflammation, infections, or monoclonal gammopathy (myeloma).
Decrease occurs in malnutrition, malabsorption, nephrotic syndrome, and severe liver disease.
Normal Ranges
| Group | Reference Range |
|---|---|
| Men | 6.4–8.3 g/dL (64–83 g/L) |
| Women | 6.4–8.3 g/dL |
| Children | 6.0–8.0 g/dL |
Reference ranges may vary by laboratory and assay method.
Causes of High Levels
- Chronic infections
- Autoimmune diseases
- Multiple myeloma
- Dehydration
Causes of Low Levels
- Malnutrition
- Liver failure
- Nephrotic syndrome
- Malabsorption syndromes
Test Preparation
- Fasting preferred
- Report chronic infections
Related Biomarkers
| Biomarker | Relationship |
|---|---|
| Albumin | Major protein fraction |
| C-Reactive Protein (CRP) | Inflammation |
| Ferritin | Chronic inflammation |
FAQ
How often should I take this test?
Annually or if myeloma/malnutrition suspected.
What should I do if my result is abnormal?
Persistent elevation — protein electrophoresis; decrease — nutrition and liver assessment.
Last updated: June 2026