Mean Corpuscular Hemoglobin (MCH)
Disclaimer: Information on this page is for educational purposes. Consult a physician to interpret your test results. Health Vault helps track biomarker trends but does not replace medical advice.
What This Test Measures
MCH (Mean Corpuscular Hemoglobin) reflects the average amount of hemoglobin in a single red blood cell, measured in picograms. It complements MCV and MCHC in anemia evaluation.
Low MCH is typical of hypochromic anemias — primarily iron deficiency. Elevation is less common and may accompany macrocytosis in B12 deficiency.
MCH is calculated automatically on CBC and helps distinguish iron deficiency from thalassemia alongside RDW and ferritin.
Normal Ranges
| Group | Reference Range |
|---|---|
| Men | 27–34 pg |
| Women | 27–34 pg |
| Children | 25–33 pg |
Reference ranges may vary by laboratory and assay method.
Causes of High Levels
- Macrocytosis with B12/folate deficiency
- Hyperthyroidism (rare)
- Newborns
Causes of Low Levels
- Iron deficiency anemia
- Thalassemia
- Chronic inflammation
- Blood loss
Test Preparation
- Standard CBC preparation
Related Biomarkers
| Biomarker | Relationship |
|---|---|
| Mean Corpuscular Volume (MCV) | Red cell volume |
| Mean Corpuscular Hemoglobin Concentration (MCHC) | Hemoglobin concentration |
| Hemoglobin | Total hemoglobin level |
FAQ
How often should I take this test?
With every CBC.
What should I do if my result is abnormal?
Low MCH with low ferritin confirms iron deficiency. Your doctor will guide treatment and follow-up.
Last updated: June 2026